Test No. 252: Rapid Estrogen Activity In Vitro (REACTIV) assay
This Test Guideline describes a Rapid Estrogen ACTivity In Vivo (REACTIV) Assay in
an aquatic assay that utilises transgenic Oryzias latipes (Japanese medaka) eleutheroembryos
at day post hatch zero, in a multi-well plate format to identify chemicals active
on the estrogen axis. The REACTIV assay was designed as a screening assay to provide
a medium throughput and short-term assay to measure the response of eleutheroembryos
to chemicals potentially active on the estrogen axis.
Published on June 25, 2024Also available in: French
In series:OECD Guidelines for the Testing of Chemicals, Section 2: Effects on Biotic Systemsview more titles