The OECD Guidelines for the Testing of Chemicals are a unique tool for assessing the potential effects of chemicals on human health and the environment.

The Guidelines are regularly updated with the assistance of thousands of national experts from OECD member countries; and are covered by the Mutual Acceptance of Data, implying that data generated in the testing of chemicals in an OECD member country, or a partner country having adhered to the Decision, in accordance with OECD Test Guidelines and Principles of Good Laboratory Practice (GLP), be accepted in other OECD countries and partner counties having adhered to the Decision.

INSTRUCTIONS AND TEMPLATE FOR SUBMISSION OF COMMENTS

• Instructions for commenting on Draft Guidance and Review Documents
• Template for submission of comments (optional)

 

CURRENT DEADLINES FOR COMMENTS

• Draft AOP 43: Disruption of VEGFR Signaling Leading to Developmental Defects 
  
• Draft AOP 277: Impaired Interleukin-1 Receptor Type I (IL-1R1) signaling leading to Impaired T-Cell Dependent Antibody Response 
  

Deadline for comments:  5 July 2023

 

• Draft Test Guideline: Determination of the Hydrophobicity Index of Nanomaterials Through an Affinity Measurement (Jan 2023) 

Deadline for comments:  9 February 2023

 

• Draft overview document supporting the prediction model update of the IL8-Luc assay (Annex 3 of TG 442E on skin sensitisation) 
• Supplementary files supporting the calculations: 
  1. Supplementary file 1
  2. Supplementary file 2 

Deadline for comments: 8 February 2023

 

• Draft Validation study report of the Epidermal Sensitisation Assay (EpiSensA) 
  Annexes 1-12 to the validation report

• Peer review report of the Epidermal Sensitisation Assay (EpiSensA)

Deadline for comments: 8 February 2023

 

• Draft Detailed Review Paper on the inclusion of thyroid endpoints in OECD fish tests

Deadline for comments: 23 December 2022

 

• Guidance on Evaluation of Data from the 8 Developmental Neurotoxicity (DNT) In-Vitro Testing 9 Battery

• Appendix A
• Appendix B1
• Appendix B2
• Appendix B3
• Appendix B4
• Appendix B5
• Appendix B6
• Appendix B7
• Appendix B8
• Appendix B9
• Appendix B10
• Appendix C
• Appendix D
• Appendix E (previous Appendix F)

Deadline for comments: 5 December 2022

 

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