Latest Documents

Draft Guidance and Review Documents/Monographs

Interested parties are invited to send their comments on the Draft AOPs 173, 346 and 376 by 13 October 2023.

OECD work on Chemical Safety and Biosafety brochure 2021-24

This new edition of the OECD work on Chemical Safety and Biosafety highlights the activities, results and ongoing projects as outlined by the 2021-2024 work programme.

OECD Work Related to Bees/Pollinators

There have been reports these last years of declines in native and managed pollinators in several regions of the world. Potential factors associated with these declines are hypothesised to include habitat destruction, predators, certain agricultural practices, bee management practices, pathogens, climate change, nutrition and pesticides. There is uncertainty regarding the extent to which pesticides contribute to pollinator declines.

Series on Testing and Assessment: publications by number

The OECD has been developing guidance documents and tools for the use of alternative methods such as (Q)SAR, chemical categories and Adverse Outcome Pathways (AOPs) as a part of Integrated Approaches for Testing and Assessment (IATA). The objective is to increase experience with the use of IATA by developing case studies, which constitute examples of predictions that are fit for regulatory use.

Section 4: Health Effects

Interested parties are invited to send their comments on draft Test Guidelines on Section 4: Health Effects.

Good Laboratory Practice (GLP)

The OECD Principles of Good Laboratory Practice (GLP) ensure the generation of high quality and reliable test data related to the safety of industrial chemical substances and preparations. The principles have been created in the context of harmonising testing procedures for the Mutual Acceptance of Data (MAD).

Ongoing Peer Reviews

Peer review package of the Test Guideline 442C Amino acid Derivative Reactivity Assay (ADRA)

Adverse Outcome Pathways, Molecular Screening and Toxicogenomics

On 11 July, the OECD released a new Adverse Outcome Pathway on Oxidative DNA damage leading to chromosomal aberrations and mutations, No. 29.

Test No. 487: In Vitro Mammalian Cell Micronucleus Test

Test No. 405: Acute Eye Irritation/Corrosion